Effects of antibiotics on Staphylococcus aureus biofilm formation associated with Peri-implantitis
##semicolon##
https://doi.org/10.5195/d3000.2023.472##semicolon##
Staphylococcus aureus##common.commaListSeparator## Biofilm##common.commaListSeparator## Peri-implantitis##common.commaListSeparator## Minimum Inhibitory Concentration要旨
One hundred and twenty specimens were collected from patients with Peri-implantitis in the period from August 2022 until September 2022 from Baquba specialized dental center, in the province of Diyala. The goal of this work was to estimate the frequency of Staphylococcus aureus and their ability to produce biofilms associated with Peri-implantitis. Also, we aimed to assess the anti-biofilm property of Ciprofloxacin and Amoxicillin/clavulanic acid on Staphylococcus aureus. The result showed growth of Staphylococcus aureus in twenty isolates (16.6%), and 95% of the Staphylococcus aureus isolates had the ability to produce biofilms. The results indicate that the minimum inhibitory concentration (MIC) of Ciprofloxacin for Staphylococcus aureus was 32 to 512 μg/ml with the sub-MIC 16 to 256 μg/ml. The MIC for Amoxicillin/clavulanic was 8 to 512 μg/ml, and the sub-MIC 4 to 256) μg/ml. Ciprofloxacin and Amoxicillin/clavulanic acid had the ability to decrease biofilm formation and Amoxicillin/clavulanic acid was more effective than Ciprofloxacin.
##submission.citations##
Lang N, Berglundh T, Periimplant diseases: where are we now?–Consensus of the Seventh European Workshop on Periodontology. Working Group 4 of the Seventh European Workshop on Periodontology. Journal of clinical periodontology.2011;38:178-181.
Berglundh, T., Armitage G, Araujo M, Avila‐Ortiz G, Blanco J, Camargo P, Zitzmann N. Peri‐implant diseases and conditions: Consensus report of workgroup 4 of the 2017 World Workshop on the Classification of Periodontal and Peri‐Implant Diseases and Conditions. Journal of periodontology.2018;89:S313-S318.
Chan H, Lin G, Suarez F, MacEachern M, Wang H. Surgical management of Peri-implantitis: A systematic review and meta‐analysis of treatment outcomes. Journal of periodontology.2014; 85(8):1027-1041.
Salvi G, Cosgarea R, Sculean A. Prevalence and mechanisms of peri-implant diseases. Journal of dental research.2017;96(1): 31-37.
Souza J, Bertolini M, Costa R , Nagay B, Dongari-Bagtzoglou A, Barão V. Targeting implant-associated infections: titanium surface loaded with antimicrobial. IScience.2021;24(1): 102008.
Spriano S, Yamaguchi S, Baino F, Ferraris S. A critical review of multifunctional titanium surfaces: New frontiers for improving osseointegration and host response, avoiding bacteria contamination. Acta biomaterialia.2018;79: 1-22.
Mombelli A, & Décaillet F.The characteristics of biofilms in peri‐implant disease. Journal of clinical periodontology.2011;38: 203-213.
Arciola C, Campoccia D, Montanaro L. Implant infections: adhesion, biofilm formation and immune evasion. Nature reviews microbiology.2018;16(7):397-409.
Marsh P, Devine D. How is the development of dental biofilms influenced by the host. Journal of clinical periodontology.2011; 38:28-35.
Almeida C, Azevedo N, Santos S, Keevil C, Vieira M. Correction: Discriminating multi-species populations in biofilms with peptide nucleic acid fluorescence in situ hybridization (PNA FISH). Plos one.2013;8(6):
Tang, J., Kang M, Chen H, Shi X, Zhou R, Chen J, Du Y. The staphylococcal nuclease prevents biofilm formation in Staphylococcus aureus and other biofilm-forming bacteria. Science China Life Sciences.2011;54(9): 863-869.
Andersson D, Hughes D. Microbiological effects of sublethal levels of antibiotics. Nature Reviews Microbiology.2014;12(7): 465-478.
Hemati S , Sadeghifard N, Ghafurian S, Maleki F , Mahdavi Z, Hassanvand A, Hatami V. The association of biofilm formation and sub-minimal inhibitory concentrations of antimicrobial agents. J Bas Res Med Sci 2016; 3(1):26-30.
Passariello C, Lucchese A, Pera F, Gigola P. Clinical, microbiological and inflammatory evidence of the efficacy of combination therapy including serratiopeptidase in the treatment of periimplantitis. European Journal of Inflammation.2012;10(3): 463-472
Canullo L, Penarrocha‐Oltra D, Soldini C, Mazzocco F, Penarrocha M, Covani U. Microbiological assessment of the implant‐abutment interface in different connections: cross‐sectional study after 5 years of functional loading. Clinical oral implants research.2015;26(4): 426-434.
Kordbacheh C, Finkelstein J, Papapanou P. Peri‐implantitis prevalence, incidence rate, and risk factors: A study of electronic health records at a US dental school. Clinical Oral Implants Research.2019; 30(4): 306-314.
Zhou, L, Li T, An J, Liao C, Li N, Wang X. Subminimal inhibitory concentration (sub-MIC) of antibiotic induces electroactive biofilm formation in bioelectrochemical systems. Water research.2017;125: 280-287.
##submission.downloads##
出版済
巻号
セクション
##submission.license##
##submission.copyrightStatement##
##submission.license.cc.by4.footer##Authors who publish with this journal agree to the following terms:
- The Author retains copyright in the Work, where the term “Work” shall include all digital objects that may result in subsequent electronic publication or distribution.
- Upon acceptance of the Work, the author shall grant to the Publisher the right of first publication of the Work.
- The Author shall grant to the Publisher and its agents the nonexclusive perpetual right and license to publish, archive, and make accessible the Work in whole or in part in all forms of media now or hereafter known under a Creative Commons Attribution 4.0 International License or its equivalent, which, for the avoidance of doubt, allows others to copy, distribute, and transmit the Work under the following conditions:
- Attribution—other users must attribute the Work in the manner specified by the author as indicated on the journal Web site;
- The Author is able to enter into separate, additional contractual arrangements for the nonexclusive distribution of the journal's published version of the Work (e.g., post it to an institutional repository or publish it in a book), as long as there is provided in the document an acknowledgement of its initial publication in this journal.
- Authors are permitted and encouraged to post online a prepublication manuscript (but not the Publisher’s final formatted PDF version of the Work) in institutional repositories or on their Websites prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work. Any such posting made before acceptance and publication of the Work shall be updated upon publication to include a reference to the Publisher-assigned DOI (Digital Object Identifier) and a link to the online abstract for the final published Work in the Journal.
- Upon Publisher’s request, the Author agrees to furnish promptly to Publisher, at the Author’s own expense, written evidence of the permissions, licenses, and consents for use of third-party material included within the Work, except as determined by Publisher to be covered by the principles of Fair Use.
- The Author represents and warrants that:
- the Work is the Author’s original work;
- the Author has not transferred, and will not transfer, exclusive rights in the Work to any third party;
- the Work is not pending review or under consideration by another publisher;
- the Work has not previously been published;
- the Work contains no misrepresentation or infringement of the Work or property of other authors or third parties; and
- the Work contains no libel, invasion of privacy, or other unlawful matter.
- The Author agrees to indemnify and hold Publisher harmless from Author’s breach of the representations and warranties contained in Paragraph 6 above, as well as any claim or proceeding relating to Publisher’s use and publication of any content contained in the Work, including third-party content.
Revised 7/16/2018. Revision Description: Removed outdated link.