Emerging Role of Viral Infection in Periodontal Disease

Autori

  • Alaa W. Izzat
  • Batool Hassan Al-Ghurabi Department of Basic Science, College of Dentistry, University of Baghdad, Ira
  • Lina Sami Adham
  • Zahraa F. Shaker

DOI:

https://doi.org/10.5195/d3000.2025.938

Parole chiave:

Periodontitis, Herpes Virus, Immune Response, Bacteria

Abstract

Periodontal disease is primarily linked to a bacterial infection, such as dental plaque, which harbors a broad microbial community and can induce numerous inflammatory responses in periodontal tissue.  In numerous instances, the local bacterial incursion and host-mediated immune reactions result in severe alveolar bone resorption. While researchers mainly concentrate on identifying periodontopathogenic bacteria, recent investigations have suggested that several viruses may also play a role in the onset and advancement of periodontitis.  Human viruses can induce cytokine release from both inflammatory and non-inflammatory cells, hence compromising periodontal immune protection. This review investigates the potential role of viral infection in the pathogenesis of periodontal disease.

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Pubblicato

2025-06-27

Fascicolo

V. 13 N. 1 (2025)

Sezione

Adults & the Elderly

Licenza

Copyright (c) 2025 Alaa W. Izzat, Batool Hassan Al-Ghurabi, Lina Sami Adham, Zahraa F. Shaker

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