Radiographic Impact of Adjunctive Chlorhexidine on Early Peri-Implant Bone Remodeling

A Randomized Controlled Clinical Trial

Autori

  • Muntathar Muhsen Abusanna University of Al-Ameed/ College of Dentistry/ Karbala, Iraq.
  • Omar Abdul Jabbar Abdul Qader

DOI:

https://doi.org/10.5195/d3000.2026.1362

Parole chiave:

Dental Implants, Oral Biofilm, Antimicrobials, Bone Loss, Periodontium

Abstract

The present study aimed to determine how chlorhexidine treatment as an additional therapy affects the first radiographic results which include marginal bone level (MBL) changes and grayscale radiographic density proxy values. The research design consisted of a prospective randomized controlled clinical study which studied 48 patients through one dental implant per participant. The investigators used random assignment to place participants into either the chlorhexidine adjunct protocol group or the standard postoperative care group. The examining team took standardized periapical radiographs at both the beginning and six months after the start of the study through a paralleling technique with established exposure settings. The MBL measurement occurred through software calibration which enabled the system to measure the distance both from the mesial and distal sides while using a specific area for grayscale density proxy analysis. The research used paired and independent tests to analyze both within-group and between-group data through repeated-measures analysis which studied time–group interactions at a significance level of p < 0.05. The two groups experienced time-dependent changes in their crestal bone structure, yet the chlorhexidine group achieved better results through its lower mean MBL change and higher grayscale density proxy values than the control group (p < 0.05). Implant survival was high in both groups, with no statistically significant difference. The measurement reliability proved satisfactory through the results of calibration testing. The using chlorhexidine as an additional treatment resulted in better initial radiographic signs of peri-implant health. The present data shows a possible biological link between treatment responses and patient results, but additional present study needs to confirm these findings by tracking patients for extended periods and measuring biological indicators.

##submission.downloads##

Pubblicato

2026-06-04

Fascicolo

V. 14 N. 1 (2026)

Sezione

Development of Craniofacial Structures

Licenza

Copyright (c) 2026 Muntathar Muhsen Abusanna, Omar Abdul Jabbar Abdul Qader

Creative Commons License

TQuesto lavoro è fornito con la licenza Creative Commons Attribuzione 4.0 Internazionale.

Authors who publish with this journal agree to the following terms:

  1. The Author retains copyright in the Work, where the term “Work” shall include all digital objects that may result in subsequent electronic publication or distribution.
  2. Upon acceptance of the Work, the author shall grant to the Publisher the right of first publication of the Work.
  3. The Author shall grant to the Publisher and its agents the nonexclusive perpetual right and license to publish, archive, and make accessible the Work in whole or in part in all forms of media now or hereafter known under a Creative Commons Attribution 4.0 International License or its equivalent, which, for the avoidance of doubt, allows others to copy, distribute, and transmit the Work under the following conditions:
    1. Attribution—other users must attribute the Work in the manner specified by the author as indicated on the journal Web site;
    with the understanding that the above condition can be waived with permission from the Author and that where the Work or any of its elements is in the public domain under applicable law, that status is in no way affected by the license.
  4. The Author is able to enter into separate, additional contractual arrangements for the nonexclusive distribution of the journal's published version of the Work (e.g., post it to an institutional repository or publish it in a book), as long as there is provided in the document an acknowledgement of its initial publication in this journal.
  5. Authors are permitted and encouraged to post online a prepublication manuscript (but not the Publisher’s final formatted PDF version of the Work) in institutional repositories or on their Websites prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work. Any such posting made before acceptance and publication of the Work shall be updated upon publication to include a reference to the Publisher-assigned DOI (Digital Object Identifier) and a link to the online abstract for the final published Work in the Journal.
  6. Upon Publisher’s request, the Author agrees to furnish promptly to Publisher, at the Author’s own expense, written evidence of the permissions, licenses, and consents for use of third-party material included within the Work, except as determined by Publisher to be covered by the principles of Fair Use.
  7. The Author represents and warrants that:
    1. the Work is the Author’s original work;
    2. the Author has not transferred, and will not transfer, exclusive rights in the Work to any third party;
    3. the Work is not pending review or under consideration by another publisher;
    4. the Work has not previously been published;
    5. the Work contains no misrepresentation or infringement of the Work or property of other authors or third parties; and
    6. the Work contains no libel, invasion of privacy, or other unlawful matter.
  8. The Author agrees to indemnify and hold Publisher harmless from Author’s breach of the representations and warranties contained in Paragraph 6 above, as well as any claim or proceeding relating to Publisher’s use and publication of any content contained in the Work, including third-party content.

Revised 7/16/2018. Revision Description: Removed outdated link.