The Effects of Selenium Nanoparticles on the Osseointegration of a Titanium Implant in Rabbits: A Histomorphometric Investigation

Auteurs-es

  • Osama A.R. Alheeti university of anbar
  • Ghasak H. Jani University of Baghdad
  • Farah Ragheed Qustanteen Al-Rasheed University college

DOI :

https://doi.org/10.5195/d3000.2024.730

Mots-clés :

Bone, Implant, Selenium Nanoparticles, Osseointegration

Résumé

Objective: One of the unique tooth or tooth replacement prosthesis in the dental implant. To encourage bone formation where it is applied, our approach uses a biomaterial system that is easily obtainable, and able to induce osteoinductive growth factor. Selenium nanoparticles are

Methods: Thirty-two implants consisting of commercially pure titanium rod were given to sixteen New Zealand rabbits. One implant was placed in each tibia of each rabbit. After implantation, eight rabbits were sacrificed every one to six weeks. For each animal, the left tibia implant was treated with selenium nanoparticles, whereas the right tibia implant was left uncoated. After staining each section with hematoxylin and eosin, the sections were examined histologically and assessed for histomorphometric analysis, which counted the number of bone particles that were formed.

Results: Selenium nanoparticle-coated titanium implants showed earlier bone growth, mineralization, and maturation than control comparisons. After all the bone parameters were examined histomorphometrically for the study, the healing durations of the two types of implants differed significantly.

Conclusion: Selenium nanoparticle-coated titanium implants had improved healing and osseointegration.

Références

Oshida Y, Tuna E, Aktören O, and Gençay K. Dental Implant Systems. Int J Mol Sci.2010; 11(4): 1580 –1678.

Papaspyridakos, P.; Mokti, M.; Chen, C. J.; Benic, G. I.; Gallucci, G. O.; Chronopoulos, V "Implant and Prosthodontic Survival Rates with Implant Fixed Complete Dental Prostheses in the Edentulous Mandible after at Least 5 Years: A Systematic Review". Clinical Implant Dentistry and Related Research. 2014.16 (5): 705–717.

Frisardi G, Barone S, Razionale AV, Paoli A, Frisardi F, Tullio A, Lumbau A, Chessa G. Biomechanics of the press-fit phenomenon in dental implantology: an image-based finite element analysis. Head and face medicine, 2012;8:18.

Belém A, Scombatti S, Martins R, Yamashina K, Iezzi G and Piattelli A. Influence of Implant Surfaces on Osseointegration. Braz Dent J, 2010; 21(6): 471-481.

Xun W, Shi L, Yue W, Zhang C, Ren Y, Liu Q. Effect of high-dose nano-selenium and selenium–yeast on feed digestibility, rumen fermentation, and purine derivatives in sheep. Biol Trace Elem Res. 2012;150(1–3):130–136.

Pi J, Yang F, Jin H, et al. Selenium nanoparticles induced membrane bio-mechanical property changes in MCF-7 cells by disturbing membrane molecules and F-actin. Bioorg Med Chem Lett. 2013;23(23):6296–6303.

Holinka, M. Pilz, B. Kubista, E. Presterl, R. Windhager(2013) .EFFECTS OF SELENIUM COATING OF ORTHOPAEDIC IMPLANT SURFACES ON BACTERIAL ADHERENCE AND OSTEOBLASTIC CELL GROWTH. THE BONE & JOINT JOURNAL VOL. 95-B, No. 5,

Depprich R, Zipprich H, Ommerborn M, Naujoks C, Wiesmann H, Kiattavorncharoen S, Lauer H, Meyer U, Kübler N and Handschel J. Osseointegration of zirconia implants compared with titanium: an in vivo study. Head & Face Medicine, 2008; 4:30.

Ibraheem NS, Al-Adili SS. Assessment of dental implant stability during healing period and determination of the factors that affect implant stability by means of resonance frequency analysis(Clinical study) . J Bagh Coll Dent [Internet]. 2015 27(3):109-15.

Al-Molla B.The effects of the Iraqi propolis on the artificial bony defects on the rabbit’s mandible. MSc thesis in oral histology, university of Baghdad. 2010.

Al-Molla B. Evaluation the effects of Amelogenin/Propolis Coating on Osseointegration of Cp Ti Implant Surface in Rabbits. 2014. Vol. 1/ Issue 3.

Osama AR Alheeti and Abdalbseet A Fatalla. Evaluation of the anti-bacterial effect of selenium

nanoparticles in peri-implantitis patients. Journal of Research in Medical and Dental Science

[eISSN No. 2347-2367 pISSN No. 2347-2545]

Ghasak H Jani, Shatha S Al-Ameer, BDS Jawad. Histological and histomorphometric analysis of strontium chloride coated commercially pure titanium implant compared with hydroxyapatite coating.J.of baghdad college of dentistry،325،2218،1-12

Téléchargements

Publié-e

2024-10-01

Numéro

Rubrique

Mechanisms of Oral Disease