A case of molar-incisor hypomineralization with genetic and environmental influences

Συγγραφείς

  • Erin Kello University of Pittsburgh, Department of Anthropology

DOI:

https://doi.org/10.5195/d3000.2017.68

Λέξεις-κλειδιά:

MIH, Molar-Incisor Hypomineralization, genetics, enamel development, case study, environmental risk factors

Περίληψη

Background: Molar-Incisor Hypomineralization (MIH) is a common childhood dental pathology. This paper describes a case with familial involvement and environmental risk factors. Case Description: A 35-year old female has yellowish-brown opacities present on central and lateral maxillary incisors, right and left maxillary canines, right and left maxillary first molars, and right and left maxillary second molars. A 33-year old male sibling has yellowish-brown opacities on the right and left central and lateral maxillary incisors. The male sibling’s fraternal twin does not have evidence of MIH. A maternal grandmother also had evidence of MIH, though involved teeth are not known. Practical Implications: MIH is a condition with both genetic and environmental components. Practitioners should consider both etiologies when patients present with the condition. 

Αναφορές

Willmott NS, Bryan RA, Duggal MS. Molar-incisor-hypomineralisation: a literature review. Eur Arch Paediatr Dent. 2008 Dec;9(4):172-9. Review. PMID: 19054470.

Weerheijm KL, Jälevik B, Ala-luusua S. Molar-incisor hypo-mineralisation. Caries Res. 2001 Sep-Oct;35(5):390-1. PMID: 11641576.

Alaluusua S. Aetiology of Molar-Incisor Hypomineralisation: A sys-tematic review. Eur Arch Paediatr Dent. 2010 Apr;11(2):53-8. Re-view. PMID:20403298.

Alaluusua S, Lukinmaa PL, Var-tiainen T, Partanen M, Torppa J, Tuomisto J. Polychlorinated diben-zo-p-dioxins and dibenzofurans via mother's milk may cause devel-opmental defects in the child's teeth. Environ Toxicol Pharmacol. 1996 May 15;1(3):193-7. PMID: 21781681.

Jälevik B, Norén JG, Klingberg G, Barregård L. Etiologic factors in-fluencing the prevalence of de-marcated opacities in permanent first molars in a group of Swedish children. Eur J Oral Sci. 2001 Aug;109(4):230-4. PMID: 11531068.

Beentjes VE, Weerheijm KL, Groen HJ. Factors involved in the aetiology of molar-incisor hypo-mineralisation (MIH). Eur J Paedi-atr Dent. 2002 Mar;3(1):9-13. PMID: 12871011

Muratbegovic A, Markovic N, Ganibegovic Selimovic M. Molar incisor hypomineralisation in Bos-nia and Herzegovina: aetiology and clinical consequences in me-dium caries activity population. Eur Arch Paediatr Dent. 2007 Dec;8(4):189-94. PMID: 18076849

: Laisi S, Ess A, Sahlberg C, Arvio P, Lukinmaa PL, Alaluusua S. Amoxicillin may cause molar inci-sor hypomineralization. J Dent Res. 2009 Feb;88(2):132-6. doi: 10.1177/0022034508328334. PMID: 19278983.

Kühnisch J, Thiering E, Heitmül-ler D, Tiesler CM, Grallert H, Hein-rich-Weltzien R, Hickel R, Heinrich J; GINI-10 Plus Study Group.; LISA-10 Plus Study Group Genome-wide association study (GWAS) for mo-lar-incisor hypomineralization (MIH). Clin Oral Investig. 2014;18(2):677-82. doi: 10.1007/s00784-013-1054-8. PMID: 23918034.

Bailleul-Forestier I, Molla M, Verloes A, Berdal A. The genetic basis of inherited anomalies of the teeth. Part 1: clinical and molecu-lar aspects of non-syndromic den-tal disorders. Eur J Med Genet. 2008 Jul-Aug;51(4):273-91. doi: 10.1016/j.ejmg.2008.02.009. Re-view. PMID: 18499550.

Jeremias F, Koruyucu M, Küch-ler EC, Bayram M, Tuna EB, Deeley K, Pierri RA, Souza JF, Fragelli CM, Paschoal MA, Gencay K, Seymen F, Caminaga RM, dos Santos-Pinto L, Vieira AR. Genes expressed in den-tal enamel development are asso-ciated with molar-incisor hypo-mineralization. Arch Oral Biol. 2013 Oct;58(10):1434-42. doi: 10.1016/ j.archoralbio.2013.05.005. PMID:23790503

Jeremias F, Pierri RA, Souza JF, Fragelli CM, Restrepo M, Finoti LS, Bussaneli DG, Cordeiro RC, Secolin R, Maurer-Morelli CV, Scarel-Caminaga RM, Santos-Pinto L. Family-Based Genetic Association for Molar-Incisor Hypomineraliza-tion. Caries Res. 2016;50(3):310-8. doi: 10.1159/000445726. PMID: 27179118.

Vieira AR, Kup E. On the Etiol-ogy of Molar-Incisor Hypomineral-ization. Caries Res. 2016;50(2):166-9. doi: 10.1159/000445128. PMID: 27111773.

Kühnisch J, Lauenstein A, Pitchika V, McGlynn G, Staskiewicz A, Hickel R, Grupe G. Was molar incisor hypomineralisation (MIH) present in archaeological case se-ries? Clin Oral Investig. 2016 Dec;20(9):2387-2393. PMID: 26780019.

Ogden AR, Pinhasi R, White WJ. Nothing new under the heav-ens: MIH in the past? Eur Arch Paediatr Dent. 2008 Dec;9(4):166-71. PMID: 19054469.

Lang J, Birkenbeil S, Bock S, Heinrich-Weltzien R, Kromeyer-Hauschild K. Dental enamel de-fects in German medieval and ear-ly-modern-age populations. An-thropol Anz. 2016 Nov 1;73(4):343-354. PMID: 27643784.

Λήψεις

Δημοσιευμένα

2017-06-08

Τεύχος

Vol 5, No 1 (2017)

Ενότητα

Mechanisms of Oral Disease

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