Physiological Status of Some Selected Salivary Antioxidants in Dental Caries

Autori

  • Sulafa Khair Al-Deen Banoosh Alayoubi University of Tikrit, College of Dentistry, Department of Basic sciences, Iraq
  • Intesar Jasim Al-Kaysi
  • Hadeel Ayad
  • Esraa Azawi

DOI:

https://doi.org/10.5195/d3000.2025.774

Parole chiave:

antioxidant, saliva, dental caries, total protein, uric acid

Abstract

Objective: Uric acid and total protein are the two main antioxidants in saliva, and dental caries is the oral disease that affects most of the total population. This study aimed to investigate the association between salivary antioxidants (uric acid and total protein) and dental caries in individuals between the ages of 20 and 30.

Materials and Methods: 50 subjects (18 males and 32 females) between the ages of 19 and 30 who attended the Efraz Health Center in Samarra city were recruited. Dental caries severity was evaluated using the DMFT and DT indices in accordance with WHO guidelines from 1997. Dental caries was divided into three categories based on scores: mild (0–10), moderate (11–20), and severe (21–and more). Salivary uric acid and salivary total protein concentration were assessed via chemical analysis of unstimulated saliva sample collection. The statistical package for social science (SPSS) version 21 was used to examine all data.

Results: Males had greater mean values for the DMFT and DT fractions than females, with the differences being statistically significant (p values of 0.05 and 0.001, respectively). Males also had higher salivary uric acid than females (P value of 0.001) and uric acid was associated with dental caries experience.

Conclusion: Salivary uric acid may act as a biomarker of dental caries. We found higher dental caries among subjects who had high levels of antioxidants.

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Pubblicato

2025-04-11

Fascicolo

V. 13 N. 1 (2025)

Sezione

Mechanisms of Oral Disease

Licenza

Copyright (c) 2025 Sulafa Khair Al-Deen Banoosh Alayoubi, Intesar Jasim Al-Kaysi, Hadeel Ayad, Esraa Azawi

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