Serum B12 and Folic Acid Level among a Sample of Iraqi Patients with Geographic Tongue

Authors

  • Noor S. Mohammed Ali *Lecturer, Department of oral diagnostic sciences, College of Dentistry, University of Baghdad.

DOI:

https://doi.org/10.5195/d3000.2025.1020

Keywords:

Geographic Tongue, Vitamin B12, Folic Acid, Anemia

Abstract

Objective: To assess the serum concentrations of vitamin B12 and folic acid in individuals suffering from geographic tongue. It also aims to investigate whether deficiencies in these hematinic nutrients are significantly linked to the occurrence of this condition.

Subjects and Methods: The data for this retrospective analysis were obtained from the medical records of individuals with oral lesions who required laboratory testing for serum B12 and folic acid between October 2024 and May 2025 due to suspected anemia. 30 patients had geographic tongue who examined by oral medicine specialist at college of dentistry/university of Baghdad and 30 healthy subjects, according to the inclusion and exclusion criteria. Statistical analysis was performed to compare mean levels between groups and to evaluate potential correlations.

Results: The average serum levels of Vitamin B12 (p < 0.001) and folic acid (p < 0.05) were significantly decreased in patients with geographic tongue compared to healthy controls. A considerable proportion of these patients had values falling below the normal reference range. These findings suggest a possible involvement of hematinic deficiencies in the underlying pathogenesis of geographic tongue.

Conclusion: The study's findings indicate that deficiencies in vitamin B12 and folic acid may contribute to the development of geographic tongue. Evaluating and addressing these nutritional gaps could be beneficial in the clinical approach to managing GT, particularly in patients presenting with symptoms. Additional longitudinal research is warranted to better understand the causal relationship and the potential benefits of targeted supplementation.

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Published

2025-09-10

Issue

Vol. 13 No. 1 (2025)

Section

Adults & the Elderly

License

Copyright (c) 2025 Noor S. Mohammed Ali

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Revised 7/16/2018. Revision Description: Removed outdated link.