Profile of Fluoride Release from a Nanohybrid Composite Resin

Authors

  • Raquel Assed Bezerra Silva Department of Pediatric Clinics, Preventive and Community Dentistry, School of Dentistry of Ribeirão Preto, University of São Paulo, Ribeirão Preto, SP, Brazil
  • Fernanda Regina Ribeiro Santos Department of Pediatric Clinics, Preventive and Community Dentistry, School of Dentistry of Ribeirão Preto, University of São Paulo, Ribeirão Preto, SP, Brazil
  • Augusto Cesar Cropanese Spadaro Department of Physics and Chemistry, School of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo, Ribeirão Preto, SP, Brazil
  • Ana Cristina Morseli Polizello Department of Physics and Chemistry, School of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo, Ribeirão Preto, SP, Brazil
  • Andiara De Rossi Department of Pediatric Clinics, Preventive and Community Dentistry, School of Dentistry of Ribeirão Preto, University of São Paulo, Ribeirão Preto, SP, Brazil
  • Marilia Rodrigues Moreira Department of Pediatric Clinics, Preventive and Community Dentistry, School of Dentistry of Ribeirão Preto, University of São Paulo, Ribeirão Preto, SP, Brazil
  • Paulo Nelson-Filho Department of Pediatric Clinics, Preventive and Community Dentistry, School of Dentistry of Ribeirão Preto, University of São Paulo, Ribeirão Preto, SP, Brazil

DOI:

https://doi.org/10.5195/d3000.2015.29

Keywords:

composite resin, sodium fluoride, glass ionomer cement

Abstract

The aim of this study was to evaluate in vitro the amount and profile of fluoride release from a fluoride-containing nanohybrid composite resin (Tetric® N-Ceram) by direct potentiometry. Thirty specimens (5 mm diameter x 3 mm high; n=10/material) were made of Tetric® N-Ceram, Vitremer® resin-modified glass ionomer cement (RMGIC) (positive control) or Filtek® Z350 nanofill composite resin (negative control). The specimens were stored individually in plastic tubes containing 1 mL of artificial saliva at 37°C, which was daily renewed during 15 days. At each renewal of saliva, the amount of fluoride ions released in the solution was measured using a fluoride ion-selective electrode with ion analyzer, and the values obtained in mV were converted to ppm (µg/mL). Data were analyzed statistically by ANOVA and Tukey’s post-hoc test at a significance level of 5%. The results showed that the resins Tetric® N-Ceram and Filtek® Z350 did not release significant amounts of fluoride during the whole period of evaluation (p>0.05). Only Vitremer® released significant amounts of fluoride ions during the 15 days of the experiment, with greater release in first 2 days (p<0.05) and stabilization in the subsequent days (p>0.05). In conclusion, the nanohybrid composite resin Tetric® N-Ceram did not present in vitro fluoride-releasing capacity throughout the 15 days of study.

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Published

2015-02-24

Issue

Vol. 3 No. 1 (2015)

Section

Infancy & Adolescence

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