Is Oral Candida associated with Dental Caries in Children - A Cross Sectional Analysis.

Authors

  • Mithun Pai Associate Professor Department of Public Health Dentistry Manipal College of Dental Sciences Mangalore
  • Shweta Yellapurkar Assistant Professor Department of Oral Pathology Manipal College of Dental Sciences Mangalore
  • Srikant Natarajan Professor and Head Department of Oral Pathology and Microbiology Manipal College of Dental Sciences Mangalore
  • Ramya Shenoy Associate Professor Department of Public Health Dentistry Manipal College of Dental Sciences Mangalore

DOI:

https://doi.org/10.5195/d3000.2022.311

Keywords:

Candida, Children, Dental caries, DMFT

Abstract

BACKGROUND: Dental caries is a world-wide public health issue and is considered the most common of all non-communicable disease. There has been a growing interest in association between oral fungal flora especially candida and dental caries. Hence the aim of the study was to assess the correlation between active caries status and oral candida carriage in children aged twelve years.

MATERIALS AND METHODS: This is a cross-sectional study where a multiphase sampling was done and a total of thirty children were selected randomly among children screened previously. Data was collected through clinical oral examinations and structured interviews. The oral rinse technique described by Samaranayake et al. was used for extracting candida spp. The correlation between candida spplevel and caries experience was performed by the Pearsons correlation coefficient.

RESULTS: The mean DMFS and defs scores of the children were 3.70±4.61 and 5.83±5.51 respectively. Significant association with decay scores for deciduous teeth (P<0.05) and defs (p= <0.001) was demonstrated. Candida species was associated highly with caries prevalence and significant positive correlation was found between Candida (CFU/plate) and defs scores (r=0.790) (p= <0.001)

CONCLUSION: The study results suggested that there is a significant positive correlation between candida carriage and caries, especially in children in the age group of 12 years.

References

Dental caries and associated factors in Ethiopia: systematic review and meta-analysis. Zewdu T, Abu D, Agajie M, Sahilu T. Environ Heal Prev Med 2021 261 [Internet]. 2021 Feb 12 [cited 2021 Jul 24];26(1):1–11. Available from: https://environhealthprevmed.biomedcentral.com/articles/10.1186/s12199-021-00943-3

Oral candidiasis: A disease of opportunity. Vila T, Sultan AS, Montelongo-Jauregui D, Jabra-Rizk MA. J Fungi. 2020;6(1):1–28.

Minimum inhibitory concentration of adherence of Punica granatum Linn (pomegranate) gel against S. mutans, S. mitis and C. albicans. Vasconcelos LCDS, Sampaio FC, Sampaio MCC, Pereira MDS V, Higino JS, Peixoto MHP. Braz Dent J. 2006;17(3):223–7.

Oral microbiome: possible harbinger for children’s health. Xiao J, Fiscella KA, Gill SR. Int J Oral Sci. 2020;12(1):1–13.

streptococcal interactions in biofilm-associated oral diseases.pdf. Koo H, Andes D, Krysan D. 2018.

Oral candidal carriage in children with and without dental caries. Uygun-Can B, Kadir T, Akyüz S. Quintessence Int (Berl). 2007;38(1):45–9.

A comparison of oral rinse and imprint sampling techniques for the detection of yeast, coliform and Staphylococcus aureus carriage in the oral cavity. Samaranayake LP, MacFarlane TW, Lamey P ‐J, Ferguson MM. J Oral Pathol Med. 1986;15(7):386–8.

Comparison of Candida species isolated from children with and without early childhood caries : A descriptive cross ‑ sectional study. Ms B, Peedikayil FC, Mb G, Tp C, Soni K, Dhanesh N. J Indian Soc Pedod Prev Dent. 2017;296–300.

The Extent of Oral Fungal Flora in 353 Students and Possible Relationships with Dental Caries. Moalic E, Gestalin A, Quinio D, Gest PE, Zerilli A, Flohic AM Le. Caries Res [Internet]. 2001 Mar [cited 2021 Jul 26];35(2):149–55. Available from: https://www.karger.com/Article/FullText/47447

Correlation between Candida spp. and DMFT index in a rural population. Cortelli SC, Junqueira JC, Faria I da S, Ito CYK, Cortelli JR. Brazilian J Oral Sci. 2006;5(17):1007–11.

Prevalence of candida albicans in oral cavities and root canals of children. Akdeniz BG, Koparal E, Şen BH, Ateş M, Denizci AA. J Dent Child. 2002;69(3):289–92.

Synergism of Streptococcus mutans and Candida albicans Reinforces Biofilm Maturation and Acidogenicity in Saliva: An In Vitro Study. Kim H-E, Liu Y, Dhall A, Bawazir M, Koo H, Hwang G. Front Cell Infect Microbiol. 2020 Feb;10.

Candida biome of severe early childhood caries (S-ECC) and its cariogenic virulence traits. Fakhruddin KS, Samaranayake LP, Egusa H, Ngo HC, Panduwawala C, Venkatachalam T, et al. https://doi.org/101080/2000229720201724484. 2020 Jan;12(1).

Association of Streptococcus Mutans, Candida Albicans and Oral Health Practices with Activity Status of Caries Lesions Among 5-Year-Old Children with Early Childhood Caries. Sridhar S, Baranya /, Suprabha S, Shenoy R, Suman E, Rao A. Oral Heal Prev Dent. 2020;18:911–9.

Oral candidal carriage and its association with dental carious lesions in asymptomatic adults: a cross-sectional study from the UAE. Al-Amad SH, Rahman B, Khalifa N, Awad MA. BMC Oral Heal 2021 211. 2021 Apr;21(1):1–6.

Downloads

Published

2022-08-31

Issue

Vol. 10 No. 1 (2022)

Section

Infancy & Adolescence

License

Authors who publish with this journal agree to the following terms:

  1. The Author retains copyright in the Work, where the term “Work” shall include all digital objects that may result in subsequent electronic publication or distribution.
  2. Upon acceptance of the Work, the author shall grant to the Publisher the right of first publication of the Work.
  3. The Author shall grant to the Publisher and its agents the nonexclusive perpetual right and license to publish, archive, and make accessible the Work in whole or in part in all forms of media now or hereafter known under a Creative Commons Attribution 4.0 International License or its equivalent, which, for the avoidance of doubt, allows others to copy, distribute, and transmit the Work under the following conditions:
    1. Attribution—other users must attribute the Work in the manner specified by the author as indicated on the journal Web site;
    with the understanding that the above condition can be waived with permission from the Author and that where the Work or any of its elements is in the public domain under applicable law, that status is in no way affected by the license.
  4. The Author is able to enter into separate, additional contractual arrangements for the nonexclusive distribution of the journal's published version of the Work (e.g., post it to an institutional repository or publish it in a book), as long as there is provided in the document an acknowledgement of its initial publication in this journal.
  5. Authors are permitted and encouraged to post online a prepublication manuscript (but not the Publisher’s final formatted PDF version of the Work) in institutional repositories or on their Websites prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work. Any such posting made before acceptance and publication of the Work shall be updated upon publication to include a reference to the Publisher-assigned DOI (Digital Object Identifier) and a link to the online abstract for the final published Work in the Journal.
  6. Upon Publisher’s request, the Author agrees to furnish promptly to Publisher, at the Author’s own expense, written evidence of the permissions, licenses, and consents for use of third-party material included within the Work, except as determined by Publisher to be covered by the principles of Fair Use.
  7. The Author represents and warrants that:
    1. the Work is the Author’s original work;
    2. the Author has not transferred, and will not transfer, exclusive rights in the Work to any third party;
    3. the Work is not pending review or under consideration by another publisher;
    4. the Work has not previously been published;
    5. the Work contains no misrepresentation or infringement of the Work or property of other authors or third parties; and
    6. the Work contains no libel, invasion of privacy, or other unlawful matter.
  8. The Author agrees to indemnify and hold Publisher harmless from Author’s breach of the representations and warranties contained in Paragraph 6 above, as well as any claim or proceeding relating to Publisher’s use and publication of any content contained in the Work, including third-party content.

Revised 7/16/2018. Revision Description: Removed outdated link.